In vivo Research Associate/ Senior Research Associate

Company: Underdog Pharmaceuticals
Location: Mountain View
Posted on: May 12, 2022

Job Description:

Underdog Pharmaceuticals is a pharmaceutical startup - developing drugs targeting the diseases and disabilities of aging. Underdog is looking for an exceptional in vivo research associate/senior research associate to join our team. Underdog is engineering drugs that can bind and reverse the pathological effects of oxidized cholesterol implicated in atherosclerosis and several other diseases of aging. Our 1st drug candidate is moving rapidly towards human clinical trials. We are in search of an in vivo research associate/senior research associate to participate in the design and execution of in vivo, in vitro, and ex vivo assays establishing safety and efficacy of compounds destined for clinical evaluation. Applicants should have a BS or MS degree in biochemistry, cell biology or a related biomedical field and substantial independent laboratory research experience (in addition to laboratory course work) with the following techniques:
Rodent handling (primarily mouse, rat experience is secondarily desirable)
Animal husbandry
Maintenance of genetic knockout strains
Normal upkeep of vivarium (cage changes, animal monitoring, etc.)
Administration of test compounds (iv, ip, sq, and im injections and oral gavage)
Blood collection (cardiac puncture, submandibular)
Necropsy (organ removal and examination, fixation of samples for histological analysis)
Rigorous upkeep of laboratory notebooks
Laboratory reagent and solution preparation
Additional experience in the following techniques will strengthen applications:
Mammalian cell culture
96-well plate assays using a plate reader spectrophotometer
Fluorescence microscopy imaging
Experience working with cholesterol and other natural and oxidized sterols
This position represents the opportunity to join a small, dynamic, interdisciplinary team and will require the following personality traits:
Excellent interpersonal and organizational skills
Ability to communicate effectively, both orally and in writing, in a cross-disciplinary team
Self-starter who can take initiative while integrating into the workflow and goals of the team
Excellent analytical and problem-solving skills
Ability to work in a collegial manner while being highly tolerant and respectful of all members of a small interdisciplinary team
Focused and goal-oriented, yet flexible enough to deal with unanticipated challenges and opportunities
Underdog Pharmaceuticals offers competitive compensation packages including salary commensurate with experience, paid vacation and sick leave, health insurance benefits, and early equity opportunities. Further information on Underdog Pharmaceuticals can be found at www.underdogpharma.com. Relocation benefits will not be provided for this position. Underdog Pharmaceuticals is an equal opportunity employer.

Keywords: Underdog Pharmaceuticals, Mountain View , In vivo Research Associate/ Senior Research Associate, Other , Mountain View, California